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69864

Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Bronchial asthma Affecting 1-18% of children in different countries, it widely distributed chronic respiratory disease. vitamin-D increase calcium absorption from the gastrointestinal tract, determines bone health and regulates neuromuscular function. In addition, vitamin-D is a potent immune system regulator, and it has a potential role in various allergic diseases.
Aim of the work: To estimate the association between asthma and Vitamin-D in pediatrics.
Patients and methods: The present work is a case control study included 150 (100 asthmatic children and 50 healthy control) children aged between 5 and 12 years. Serum 25- hydroxy vitamin-D levels were evaluated and compared between two groups. Association between vitamin-D and pulmonary function was studied in asthmatic children.
Results: Cases had significantly lower values of FEV1%, FEV1/FVC ratio and vitamin-D levels when compared to controls (53.20±6.27, 68.64±4.42, 24.44±20.92 vs 126.44±10.15, 107.20±5.05 and 84.25±41.79 successively). In addition, vitamin-D was positively and significantly correlated with pulmonary function tests (FEV1% and FEV1/FVC ratio).
Conclusion: Children with bronchial asthma suffered from marked reduction of vitamin-D which correlated with asthma severity.

DOI

10.21608/ijma.2020.14621.1018

Keywords

bronchial asthma, children, Lung function, Vitamin-D, correlation

Authors

First Name

Magdy

Last Name

Sakr

MiddleName

-

Affiliation

Department of Pediatrics , Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

sakrmagdy@hotmail.com

City

Cairo

Orcid

-

First Name

Mohamed

Last Name

Elsamnody

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

mohamed_elsamnody@yahoo.com

City

-

Orcid

-

First Name

Atef

Last Name

Elrifai

MiddleName

-

Affiliation

Department of Chest Disease, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

atefchest@domazhermedicine.edu.eg

City

-

Orcid

0000-0003-4953-4997

First Name

Hesham

Last Name

Abd-Al-Samee

MiddleName

-

Affiliation

Department of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

dr.hesham012@gmail.com

City

-

Orcid

27608151100155

First Name

Ahmed

Last Name

Saad

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

ahmedarafasaad@gmail.com

City

-

Orcid

0000-0002-2973-6965

Volume

2

Article Issue

1

Related Issue

10770

Issue Date

2020-01-01

Receive Date

2019-09-03

Publish Date

2020-01-01

Page Start

308

Page End

312

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 1_Pages 308-312.pdf

PDF . 265.9kB

Link

https://ijma.journals.ekb.eg/article_69864.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=69864

Order

21

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023