In this paper, a model was developed based on simple equations to design a surface flow constructed wetland system (SFCWL). The hydraulics of the system and the pollutant removal were based on first-order plug flow assumptions (k-C* model) to remove biological oxygen demand (BOD), fecal coliforms (FC), total suspended solids (TSS), total nitrogen (TN) and total phosphorus (TP). In addition, the (SFCWL) hydrology was considered. The model was applied to design a new (SFCWL) of vegetated cells (reed) followed by a storage pond system to treat 6000 m3/day of the degraded agricultural drainage water in the East South EL-Kantara region, North Sinai, Egypt. The model input data were summer air temperature 27 oC, winter air temperature 15 oC and influent concentrations for (BOD) 120 mg/L, (FC) 100000 CFU/100 mL, (TSS) 155 mg/L, (TN) 20 mg/L and (TP) 5 mg/L. The model output showed 3.54 days retention time and the total area of the system, including storage pond was 25.7 hectares. The expected overall pollutant removal efficiencies for (BOD), (FC), (TSS), (TN) and (TP) were 83.3%, 99.5%, 88.6%, 66% and 50% respectively. The proposed (SFCWL) system as a promising low-cost treatment alternative can change polluted agriculture drainage water to an unconventional water source that will be utilized for irrigation and environment-friendly.