Interstitial lung disease includes a wide range of pulmonary diseases associated with varying clinical appearance, therapeutic response and prognosis which are a real challenge for diagnoses. The aim of this study is to described the different histopathological patterns in interstitial pneumonia of camels slaughtered in Draw abattoir in Aswan government to provide clinicians with information on the pathological features of interstitial pneumonia, which in most cases may allow for a specific diagnosis and a careful correlation with clinical findings. Also, a pattern-based histopathological approach to interstitial lung disease can help guide clinicians in choosing suitable treatment and provide camel owners with correct prognoses. A total of 42 lungs of camels were examined for histopathological changes. 30 cases of Interstitial pneumonia were detected among the 42 examined camels' lungs. Interstitial pneumonia in camels has variable pathologic pictures. Fibrotic and cellular interstitial pneumonia are considered as the two main histologic subtypes. Nodular patterns were recognized as uncommon histologic changes. This study concluded that cellular, fibrotic and nodular forms are the common patterns of interstitial pneumonia in camels