An experiment was conducted on 210 healthy one day old broiler chicks to evaluate the effect of synbiotics and/ or essential oils on induced necrotic enteritis (NE) and coccidiosis. The treated groups were, 1) ABAC group: challenged and fed basal diet with antibiotic and anticoccidial drugs; 2) SY group: challenged and fed basal diet with synbiotic; 3) EO group: challenged and fed basal diet with essential oils (EO); 4) SYEO group: challenged and fed basal diet with combination of synbiotics and essential oils; 5) CO group: fed basal diet and challenged with Eimeria spp.; 6) NE group: fed basal diet and challenged with Eimeria spp. + C. perfringens, and 7) CN group: fed basal diet. All additives were given from 0 day (d) to 35 d. The results showed positive impact of synbiotic and EO treatments on lesion scoring and C. perfringens quantification in comparison with challenged non treated groups. The body weight did not show significant improvement (P>0.05) in SY group but the EO group increased the BW (P>0.05). The treatments significantly decreased the oocyst shedding, dropping scoring and litter scoring against coccidiosis infection in comparison with NE group (P<0.05). The ABAC group showed insignificant decline in the aforementioned parameters in comparison with synbiotic and EO treatments (P>0.05). All treatments significantly improved the histopathological lesion scoring of intestine and liver as well as the coccidial infection score (P<0.05). Our data suggest that synbiotic and essential oils may be used as promising alternatives for antibiotic and anticoccidial feed additives.