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32752

Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines

Article

Last updated: 04 Jan 2025

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Abstract

Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of clovenhoofed
animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGY-A-2012) and
imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid
control of the disease. Our study aimed to determine the antigenic relatedness (R-value) of FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines
using serum neutralization test (SNT). At 28th day post vaccination with either local commercial or imported
vaccines, the calculated R-values for O/EGY-4-2012 were 0.84 with O Panasia-2 in local commercial
vaccine and 0.65 with O Manisa in imported vaccine. A/EGY/1/2012 showed R-value 0.78 and 0.72 with
A Iran-05 in local commercial and imported vaccines respectively. In conclusion, FMD virus Egyptian
isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported
vaccines, which provide good protection.

DOI

10.21608/bvmj.2015.32752

Keywords

Foot-and-mouth disease, R-value, serotypes O and A, vaccinal strains

Authors

First Name

Gabr

Last Name

El-Bagoury

MiddleName

F.

Affiliation

Department of virology, Faculty of Veterinary Medicine, Benha University

Email

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City

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Orcid

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First Name

Saad

Last Name

Sharawi

MiddleName

S.A

Affiliation

Department of virology, Faculty of Veterinary Medicine, Benha University

Email

-

City

-

Orcid

-

First Name

Ehab

Last Name

El-Nahas

MiddleName

M.

Affiliation

Department of virology, Faculty of Veterinary Medicine, Benha University

Email

-

City

-

Orcid

-

First Name

Darwish

Last Name

Darwish

MiddleName

M.

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo

Email

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City

-

Orcid

-

First Name

Mohammed

Last Name

Saad

MiddleName

A.

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo

Email

-

City

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Orcid

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Volume

28

Article Issue

1

Related Issue

5511

Issue Date

2015-03-01

Receive Date

2019-05-22

Publish Date

2015-03-01

Page Start

235

Page End

240

Print ISSN

1110-6581

Link

https://bvmj.journals.ekb.eg/article_32752.html

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https://bvmj.journals.ekb.eg/service?article_code=32752

Order

27

Type

Original Article

Type Code

812

Publication Type

Journal

Publication Title

Benha Veterinary Medical Journal

Publication Link

https://bvmj.journals.ekb.eg/

MainTitle

Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines

Details

Type

Article

Created At

22 Jan 2023