The main purpose of this study is to examine the relationship between talent management strategies and employee performance at five and four star hotels in Cairo city which is a major tourism destination in Egypt. The field study was done by using questionnaire forms, which were distributed to 294 human resource managers in the investigated hotels in addition to pre-planned interviews with hotel executives. Data were analyzed by using "Statistical Packages for Social Science" - SPSS software version 22. The findings of this study showed that there are significant and positive relationships between talent management variables (i.e., talent planning, developing & attracting, workplace culture, recruitment & retention, and rewarding) and employee performance dimensions (i.e., financial prospective, internal process prospective, & guest prospective). The study shows that the talent management practices are still at the beginning stage, due to the formal interest in human resources and the focus on traditional roles for them without considering the strategic dimension of the talent management in formulating the steps for success and excellence to the hotels. The study suggests that talent management should be included in the organizational chart of the hotel due to its ability to maximize the profitability through playing a vital role in employee engagement, lower recruitment costs and long-term competitiveness of the hotel.