A total of 28767 cows; 14499 buffaloes; 145 camel and 2338 sheep were slaughtered during the period January 2020 to December 2021 at seven abattoirs in Markaz Ashmoon, Monufia Governorate, Egypt to assess the prevalence of Cysticercosis, Hydatidosis, Sarcocystosis and Fascioliasis infections in the slaughtered animals. The prevalence of Cysticercus bovis in slaughtered cows and buffaloes were 68 (0.24%) and 160 (1.1%), respectively. while the prevalence Sarcocystis were 36 (0.13%), and 90 (0.62%) respectively, and in Fasciola were 84 (2.9%), 65 (0.45%) and 35 (1.49%) in slaughtered Cows, Buffaloes and Sheep, respectively. Meanwhile the prevalence of Hydatid cysts were 18 (12.4%) and 13(0.55%) in slaughtered camel and sheep, respectively. The total prevalence of Cysticercus bovis, which spp Sarcocystis spp., and Hydatid Cysts in relation to the total slaughtered animals and to the total infected animals were 0.5% - 40% ; 0.4% -32.33%; 0.28% -22.14% and 0.06% -5.4% respectively. The total economic losses as a result of parasitic infestation reached 111040 LE.