BBackground: Perimembranous ventricular septal defect (pmVSD) is the most encountered form of VSD. Transcatheter closure of pmVSD in suitable candidates is an appealing alternative to surgical closure with equivalent success and major complications rates; however, with shorter hospital stay and better cosmetic outcome. The Nit Occlud® Lê VSD coil (pfm medical, KÖln, Germany) has been designed for percutaneous VSD closure.
Aim: The purpose of this study is to evaluate the safety and efficacy of pmVSD closure with Nit Occlud® VSD Lê coil.
Subjects and methods: Patients diagnosed with pmVSD and eligible for percutaneous closure with Nit Occlud® VSD Lê coil were recruited and followed for 6 months.
Results: 16 patients (median ( IQR) age 6 (3.8-9.1) years, 68.75% females) who underwent percutaneous pmVSD closure with Nit Occlud® VSD Lê coil and completed 6-months follow-up were enrolled in the study. The procedure was successful in all patients with no major complications requiring device retrieval. Median procedure time was 57 minutes and median fluoroscopy time was 24 minutes. The immediate complete occlusion rate was 31.25%, which increased to 75% after 6-months. One patient (6.25%) developed transient 2:1 AV block. One patient (6.25%) developed hemolysis that resolved after the implantations of two vascular plugs. One patient (6.25%) developed mild aortic regurgitation and 2 patients (12.5%) developed mild tricuspid regurgitation
Conclusions: Percutaneous pmVSD closure using Nit Occlud® Lê VSD coil is feasible, safe and efficacious in selected patients. It may be a suitable alternative for surgical closure in appropriate candidates.