Abstract:
Background:
Hepatocellular carcinoma is the most common primary malignancy of the liver and one of the most frequent causes of death in patients with liver cirrhosis.
In Egypt it is one of the most challenging tumors with high incidence, prevalence and mortality rates .
The degree of liver fibrosis is the strongest indicator of risk for HCC development, that's why liver stiffness measured by TE is useful in demarcating patients at a high risk for HCC, who require frequent check-up by imaging examinations.
Aim of work:
The aim of this study was to study the role of US elastography (FibroScan) in early detection of HCC in cirrhotic patients in comparison with triphasic CT.
Patient and methods:
This study was conducted on 100 patients with liver cirrhosis, 50 of them had HCC. All the patient was diagnosed with liver cirrhosis by US examination and underwent fibroscan to estimate the degree of fibrosis and then triphasic CT to confirm or exclude the presence of HCC.
Results:
There is a correlation between high TE results and the incidence of HCC detection by CT, HCC detection was (100%) in the groups with LSM value (>30KPa) and low (9.6%) in the group with LSM value (15-25KPa).
Conclusion:
The higher LSM the more liability for the patient to have HCC on CT scanning.
Keywords: Hepatocellular carcinoma, transient elastography, triphasic CT, liver stiffness measurment.