ROLE OF MRI DIFFUSION IN DIFFERENTIATION BETWEEN BENIGN AND MALIGNANT PAROTID GLAND TUMORS


Abstract

Background:The potential additional value of diffusion in oncological imaging lies in the fact that it provides functional tissue information, which can be combined with anatomical MR images to improve the specificity of lesion characterization.The DWI studies and ADC measurements provide useful information about tumor cellularity that can correlate with the histological pattern of parotid lesion and give a clue in differentiation between benign and malignant tumors

Aim of work:this work aims to study the value of the diffusion weighted imaging and ADC measurement coupled with a high-resolution MR imaging technique that can enable effective characterization of histologic features of the parotid tumors. We also expected that mapping of the ADC could differentiate benign from malignant tumors

Patients and methods: This study included 25 (14female and11 male) . Patients ages ranged from 3–69 year old . All the patients presented to the "National Cancer Institute" during the past year.

Results: combining DWI and ADC values has increased accuracy, as the sensitivity and specificity were 92.86%, 90.91% respectively with 92.86% positive predictive value and 90.91% negative predicative value



Conclusion: our date and in agreement with previous studies had demonstrated that determining whether a parotid gland tumor is benign or malignant on the basis of combining morphologic features and DWIs & ADC measurements in a diagnostic noninvasive approach are very promising and might decrease number of unnecessary invasive procedures

Keywords: MRI diffusion, ADC , parotid tumors