Introduction
We explored the diagnostic value of a urine soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) for early sepsis identification, severity and prognosis assessment, and for secondary acute kidney injury (AKI). We compared this with white blood cell (WBC) counts, serum C-reactive protein (CRP), urine output, creatinine clearance (CCr), serum creatinine (SCr), and blood urea nitrogen (BUN).
Methods
This case control study will be conducted on 50 critically ill children with sepsis admitted to PICU and 20 healthy children as control group.
Study group will be classified as follows :
I. Patients :
- group (A) : Septic patients with AKI
- group (B) : Septic patients without AKI
II. Control group (20) with the same age&sex
Results for urine Strem-1,CBC,CRB and S.Creatinine were recorded on day 1
Results
There were no significant differences between all groups as regard age & gender. P values were 0.43 & 0.709 respectively
sTREM-1 showed overall significant difference between all groups (P value