Background: Laparoscopic appendectomy combines the advantages of diagnosis & treatment in single procedure with least morbidity. In addition, whole abdomen can be visualized to rule out other coexisting pathology. Patients are likely to have less postoperative pain and be discharged from hospital and return to activities and routine work sooner than those who have undergone open appendectomy. Aim of the work: The purpose of the work was to describe our experience in comparative evaluation of modified laparoscopic versus open appendectomy for the treatment of acute appendicitis as regard surgical techniques, operative time and hospital stay in young females. Methodology: Our retrospective study has been conducted in General Surgery Department of Benha University Hospital from Oct 2017 to March 2018 on 40 patients. Results: Our results showed that laparoscopic appendectomy has many advantages such as: shorter hospital stay, decreased need for postoperative analgesia, earlier return to  work and  lower  rate  of  wound  infection.  Conclusion: Laparoscopic appendectomy is safe and effective, less postoperative pain, early return to normal work and better cosmetic scar than open appendectomy.