ABSTRACT
Background: Toxoplasmosis is a worldwide parasitic disease resulting from the protozoan parasite Toxoplasma gondii; an obligatory intracellular parasite that belongs to the phylum Apicomplexa infecting nearly one-third of humans, with possible excessive consequences in neonates and immunocompromised patients. Acute on top of chronic exacerbation of infection is very dangerous when immunity drops. Current treatment programs consist of using conventional chemical compounds or herbal compounds which have restricted entry to the brain, despite their high harmlessness to the host. Enhancements are wished in treatment programs and formulations to deal with those infections and to allow the medication to cross the central nervous system. Different forms of nanomaterials are utilized in nanotechnology and are composed of numerous constituents, involving polymers, lipids, and metals. The reduced size of nanoparticles allows them to enter the blood-brain barrier leading to extra activity. Metal nanoparticles, for example, silver and gold, reveal anti-parasitic activities. This study aims to spotlight the therapeutic effect of nanoparticles on toxoplasmosis.