Diabetes is frequent among cirrhotic patients. Hepatic encephalopathy and hepatocellular carcinoma, ascites, renal dysfunction, and bacterial infections are all possible complications. Diabetes is hypothesized to play a part in the advancement of fibrosis and cirrhosis, Additionally to NAFLD, by regulating multiple critical fibrogenesis mechanisms. Hyperglycemia is a significant predictor marker in people with cirrhosis, indicating an increased chance of death. When diabetes mellitus (DM) is first identified, its treatment should be incorporated into the patient's entire treatment plan. To reduce the danger of liver failure-related consequences and slow the advancement of chronic liver disease. End-stage renal disease is a frequent consequence of patients with liver cirrhosis, which is correlated to raised mortality and morbidity. patients with preexisting DM have a roughly doubled danger of hepatocellular carcinoma and HCC-related death. whatever the cause of the underlying CLD, HCC has a terrible prognosis, with a median survival of months.

Keywords:
Diabetes mellitus, renal failure, liver cirrhosis, hepatic encephalopathy.