ABSTRACT:
Introduction: The thyroid gland is very important gland to our body health, The thyroid gland uses iodine from the foods to make two main hormones: thyroxin and triiodothyronine. Thyroid hormones affect every cell and all the organs of the body as They Regulate the rate at which calories are burned, affecting weight loss or weight gain and Can slow down or speed up the heart beat.
Aim of work: The study aimed to investigate soybean meal effect on the histological structure of the thyroid gland.
Material and method: For this purpose, 30 male albino rats were divided into two groups each of 15 rats, as following (G1): normal control rats, , were provided with water and food ad libitum (G2): were given high dose of soybean meal (40%) from the daily diet from Postnatal Day "PND" 21. For each group animals were scarified at the age of 6 weeks.

Results: The results concluded that consumption of soybean at pre pubertal life stage decreased thyroid gland activity .

Conclusion :The present study concluded that high doses of the soybean adversely affect the thyroid gland structure and function at prepubertal life stage.
Keywords: Soybean, Histology, Function, Thyroid, Puberty.