157015

Aggressive Giant Cell Reparative Granuloma of the Hard Palate with invasion of the Nasal Cavity.

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Otolaryngology.

Abstract

While seldom seen, giant cell reparative granuloma (GCRG) is a benign lesion; it can affect the area of the head and neck, primarily in the mandible and less frequently in the maxilla. In the first three decades of life, GCRG typically grows, but can be seen at any age, and seen more often in women than in men. It can be locally aggressive with bone degradation and loss of teeth, although its benign nature. A 16-year-old female patient was admitted to our clinic with symptoms of FB sensation in the roof of her mouth with palatal swelling that she had noticed 3 months ago, along with nasal obstruction mostly on the right side. In the physical examination, a 2.5 cm × 3 cm sized mass was located in the midline of the hard palate. Under general anesthesia, Surgical excision was done through a transoral approach with safety margins. Buccinator muscle flap was harvested and repair of the defect of the hard palate and nasal floor was done and the operation was finished successfully. Histopathological examination shows a high number of giant cells in a stroma rich with fibroblasts and a lesion of new bone formations. Upon these findings, the case was diagnosed with GCRG‏. Post-operative follow-up, it was found that the epithelization process was complete and the defect was healed with no recurrence.

DOI

10.21608/smj.2021.46776.1207

Keywords

Giant cell, reparative granuloma, Hard palate

Authors

First Name

khaled

Last Name

dahy

MiddleName

gamal

Affiliation

otorhinolaryngology faculty of medicine sohag university egypt

Email

khgamal@kuhp.kyoto-u.ac.jp

City

-

Orcid

-

First Name

ahmed

Last Name

ismail

MiddleName

-

Affiliation

otorhinolaryngology faculty of medicine sohag university egypt

Email

anahas29@gmail.com

City

-

Orcid

-

First Name

doaa

Last Name

gad

MiddleName

mohamed

Affiliation

Otorhinolaryngology Faculty of medicine Sohag university Sohag Egypt

Email

doaagad73@gmail.com

City

-

Orcid

-

First Name

arafat

Last Name

mohamed

MiddleName

-

Affiliation

otorhinolaryngology faculty of medicine sohag university egypt

Email

dr.arafatent@gmail.com

City

-

Orcid

0000-0003-2390-7943

First Name

mahmoud

Last Name

sobhy

MiddleName

-

Affiliation

maxilofacial surgery sohag university

Email

m.s.allam@gmail.com

City

-

Orcid

-

First Name

Farghali

Last Name

Mekki

MiddleName

Abd Elrahman

Affiliation

Otorhinolaryngology Faculty Of Medicine Sohag University Sohag Egypt

Email

farghalimekki2@gmail.com

City

Sohag

Orcid

-

Volume

25

Article Issue

1

Related Issue

18599

Issue Date

2021-01-01

Receive Date

2021-01-02

Publish Date

2021-01-01

Page Start

96

Page End

102

Print ISSN

1687-8353

Online ISSN

2682-4159

Link

https://smj.journals.ekb.eg/article_157015.html

Detail API

https://smj.journals.ekb.eg/service?article_code=157015

Order

14

Type

Original Article

Type Code

785

Publication Type

Journal

Publication Title

Sohag Medical Journal

Publication Link

https://smj.journals.ekb.eg/

MainTitle

Aggressive Giant Cell Reparative Granuloma of the Hard Palate with invasion of the Nasal Cavity.

Details

Type

Article

Created At

22 Jan 2023