Recently the world faces a pandemic of infection with the new coronavirus which discovered first in Wuhan, China, in December 2019, which lead to a wide variety of symptoms ranging from mild symptoms to marked respiratory distress and pneumonia of unexplained etiology, it cause terrorism all over the world. According to the world health organization, it is considered an international public health emergency. Infection with the new coronavirus is considered one of the most common widespread infectious diseases in addition to viruses like SASR and MERS. although coronaviruses mostly infect the respiratory system, Viral shedding may, unfortunately, occur in blood, so there is a risk of transmission of coronavirus by blood transfusion, this will be a major problem for patients depending on repeated blood transfusions such as cancer patients, blood disorders patients and pregnant women in need for blood transfusion so special considerations should be given to the safety of blood transfusion especially with the appearance of asymptomatic carriers.