The fast invasion of coronavirus pandemic (COVID-19) attributed to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is becoming international major health problem. It has been defined as a pandemic by the World Health Organization (WHO) in March this year. Nearly all COVID-19 patients have dyspnea as the most prominent symptom. Neurologic manifestations may also present such as anosmia, headache, confusion, encephalitis Guillain Barre syndrome and cerebrovascular stroke. Coronaviruses are well known to be neuroinvasive. Accumulating proof is present that coronaviruses disease is not consistently restricted area of respiratory system. The nervous system may be involved in vulnerable patients and may cause severe complications and death. Post-infectious, autoimmune complications in the recovery period may also happen. It is of highly importance to understand and identify neurologic burden of to help treatment strategies as the current pandemic continues to grow. Many recent reports confirmed central nervous system involvement in COVID-19 infected patients. We will try to explore the neurologic symptoms and complications of the new mysterious outbreak.