OBJECTIVES:
To evaluate the feasibility and safety of Ultrasound-guided radiofrequency ablation in the treatment of women with symptomatic uterine fibroids.
DESIGN:
Prospective interventional clinical trial study.
METHODS:
Forty women with symptomatic uterine fibroids underwent Ultrasound-guided radiofrequency ablation. Primary Outcome measures are changes in fibroid-related symptoms and tumor size after the procedure measured at baseline, 3 and 6 months after the intervention. Secondary Outcome measures are recurrence of fibroid symptoms following the procedure ( Time Frame: Baseline to 6 months ) and operative complications ( Time Frame: Baseline to 6 weeks ).
RESULTS:
The 40 patients, fulfilled the follow-up evaluations post-ablation. The mean uterine fibroid volume reduction rate was 40% at 3 months and 60% at 6 months post-ablation. symptoms, especially bleeding were statistically significantly declined. No severe complications such as penetration or burn injuries of the nearby organs were detected.
CONCLUSION:
Ultrasound-guided radiofrequency ablation is effective in reducing fibroid symptoms and size. Ultrasound-guided radiofrequency ablation ablation is a promising new treatment option for Leiomyomas and should be further evaluated.