Background: Hepatorenal syndrome is a clinical condition that occurs in patients with chronic liver disease, advanced liver cell failure and portal hypertension characterized by impaired renal function Various variables were studied between survivor and non-survivor groups to detect possible predictors of non-survival .
Objective: This study aims to assess outcome of hepatorenal syndrome in Sohag University Hospitals and discover possible predictors of non-survival in these patients.
Materials & Methods : This study included 50 patient attented Sohag University hospital from 1 / 4 / 2017 till 1 / 10 / 2017 and Who agreed to share in the study and fulfilling the criteria of hepatorenal syndrome were be studied prospectively to observe clinical outcome Various variables were studied between survivor and non-survivor groups to detect possible predictors of non-survival in hepatorenal syndrome. The diagnosis for cirrhosis was based on history, examination, liver function test, and abdominal ultrasound. In all patients history of jaundice, fever, abdominal pain, abdominal distension, deceased urine output and GIT bleeding was  taken. diagnosis of hepatorenal syndrome was according to the International Ascites club criteria (inclusion criteria).Study was divided into 2 groups, survivors and non-survivors.
Results: the study shows 14 patients (28%) were survivors, but the remaining 36 patients were non-survivors (72%). the possible predicting factors of mortality  included were male sex,having tense ascites, having SBP,hepatic encephalopathy being child score C, type I HRS,with high level ofserum creatinine and urea,low level of serum albumin. These factors were be subjected to multivariate regression analysis.