Background: Individuals who actively engage in drug use can become exposed to potentially traumatic events as a result of the consumption and acquisition of drugs as both tend to nurture violent and criminal activity.
Materials and methods: this cross-sectional study conducted on 300 trauma victims of both sexes, admitted to Sohag University hospitals .Urine samples were taken from all patients immediately after admission. Urinary samples were tested by Immunoassay (ABON™ Multi-Drug) which is one step screen test panel used for qualitative detection of drugs of abuse which includes (Tramadol, Opiate, THC, Amphetamine, Barbiturate, Benzodiazepines).Only positive cases were confirmed by drug analyzer.
Results: Of the 300 patients 82 patients were moderately injured and only two patients were severely injured .Of the 300 patients 46 (15.3%) tested positive for one or more drugs. The drugs most commonly detected were tramadol (26patients, 8.3%), cannabinoids (14patients, 4.6%), Benzodiazepines (10, 3.3%) and opium (2 patients, 0.6%).
 Conclusions: drug abuse is a common cause of trauma.