Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune systemic inflammatory multisystem disease of unknown cause marked by symmetric, peripheral polyarthritis The prevalence of GERD began to increase from the end of the 1990s, and is now very common, especially in the elderly  population, ranging from 1.4% to 52.1% in the literature, Furthermore, GERD often accompanies many chronic diseases such as diabetic mellitus (DM), chronic liver disease, obstructive sleep apnea syndrome (OSAS), and bronchial asthma.
Aim of the work: To assess  the prevalence of GERD symptoms in patients with   Rheumatoid     arthritis (RA).
Patients and Methods: Case control study, included 100 adult rheumatoid arthritis patients and 25 age and sex matching control patients  recruited from rheumatology out patient clinics in Sohag university hospital diagnosed according to the European League Against Rheumatism (EULAR) classification criteria 2010 for RA.
Results: Rheumatoid arthritis can be considered as an independent risk factor for GERD. Disease activity could not be considered as risk factor for GERD
Conclusion: Our results showed that in the present group of RA patients mean of GERD questionnaire was 10.4 which is higher in case group than control group with significant difference