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42049

Association of osteopontin promoter polymorphism and aggresivness in breast cancer

Article

Last updated: 04 Jan 2025

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Abstract

Osteopontin (OPN) is an extracellularmatrix protein that is overexpressed in various cancers and promotes oncogenic features including cell proliferation, survival, migration, and angiogenesis, among others. OPN can participate in the regulation of the tumor microenvironment, affecting both cancer and neighboring cells. Here, we review The role of single-nucleotide polymorphism (SNP)-443 of the OPN gene in cancer aggressiveness.

DOI

10.21608/smj.2018.42049

Authors

First Name

Madeha

Last Name

Zakhary

MiddleName

M.

Affiliation

Department, of Medical Biochemistry, Faculty of Medicine, Assuit university.

Email

-

City

Assuit

Orcid

-

First Name

Aida

Last Name

Mahmoud

MiddleName

A.

Affiliation

Department, of Medical Biochemistry, Faculty of Medicine, Sohag university.

Email

aida_mahmoud@med.sohag.edu.eg

City

Sohag

Orcid

-

First Name

Wael

Last Name

Ahmed

MiddleName

B.

Affiliation

Department of General Surgery, Faculty of Medicine, Sohag university.

Email

-

City

Sohag

Orcid

-

First Name

Marwa

Last Name

Hashim

MiddleName

shaaban

Affiliation

Department of Biochemistry and microbiology, Facaulty of Medicine, Sohag University.

Email

marwa_hashem@med.sohag.edu.eg

City

Sohag

Orcid

-

Volume

22

Article Issue

1

Related Issue

4799

Issue Date

2018-01-01

Receive Date

2018-11-06

Publish Date

2018-01-01

Page Start

375

Page End

379

Print ISSN

1687-8353

Online ISSN

2682-4159

Article File

SMJ_Volume 22_Issue 1_Pages 375-379.pdf

PDF . 78.7kB

Link

https://smj.journals.ekb.eg/article_42049.html

Detail API

https://smj.journals.ekb.eg/service?article_code=42049

Order

53

Type

Original Article

Type Code

785

Publication Type

Journal

Publication Title

Sohag Medical Journal

Publication Link

https://smj.journals.ekb.eg/

MainTitle

Association of osteopontin promoter polymorphism and aggresivness in breast cancer

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Type

Article

Created At

22 Jan 2023