Infertility considered a big health problem with increasing prevalence, having several causes, some of these causes refer to adipose tissue abnormalities.
Many substances secreted from white adipose tissue like leptin ,visfatin may have a role in several cases in infertility in women
Objective:to answer questions concerned with the relation between lepin ,visfatin and omen's infertility  through analysis of data from previous studies.

Thwe strategy of this systematic review will be based on raising some research questions that give an idea about the relationship between leptin and visfatin level and women infertility.
لإhe research questions
1-Is there a relationship between obesity and infertility in women?
2-Is there a relationship between obesity and leptin and visfatin level ?
3- Is there a relationship between leptin and visfatin level and infertility in women  ?
4-Is there a difference in leptin ,visfatin level between obese and non obese infertile women ?
5-How does leptin ,visfatin affect women's fertility?