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37450

The Preventive Effects of Adrenalectomy in Metha- nol Intoxication on Photoreceptors in Rabbit Retina (Oryctolagus cuniculus): Ultrastructural Study

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Last updated: 22 Jan 2023

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Abstract

In this work the protective effect of adrenalectomy against the methanol intoxication in photoreceptor layer of rabbit retina was studied. Fifteen female White New Zealand rabbits were used in this study, and were divided into three groups: Control group, Experimental group I (re- ceived 4 gram/ kilogram methanol), Experimental group II (adrenalec- tomized and received 4 gram/kilogram methanol). Then af- ter, the retina was separated and observed by transmission electron microscope.
The major sign of pathology such as outer segment loss, disorganized inner segment and condensed and pyknotic nuclei in outer nuclear lay- er of photoreceptor layer were seen in experimental group I. But normal photoreceptor layer were obvious in adrenalectomized animals in exper- imental group II.
These observations showed that the adrenalectomy could improve the damage of the photoreceptor layer of the retina against the oxidative stress of methanol intoxication.

DOI

10.21608/jva.2016.37450

Keywords

Photoreceptor layer, Methanol, Adrenalectomy, Rabbit

Authors

First Name

A.

Last Name

Esfandiari

MiddleName

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Affiliation

Department of Basic Sciences of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran.

Email

esfandiari.arash@gmail.com

City

Kazerun, Iran

Orcid

-

First Name

A.

Last Name

Aliabadi

MiddleName

-

Affiliation

Department of Surgical Sciences of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran.

Email

-

City

Kazerun, Iran.

Orcid

-

Volume

9

Article Issue

1

Related Issue

6041

Issue Date

2016-04-01

Receive Date

2016-01-26

Publish Date

2016-04-01

Page Start

63

Page End

70

Print ISSN

1687-9988

Online ISSN

2357-0504

Article File

JVA_Volume 9_Issue 1_Pages 63-70.pdf

PDF . 1.4MB

Link

https://jva.journals.ekb.eg/article_37450.html

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https://jva.journals.ekb.eg/service?article_code=37450

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5

Type

Original Article

Type Code

782

Publication Type

Journal

Publication Title

Journal of Veterinary Anatomy

Publication Link

https://jva.journals.ekb.eg/

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Article

Created At

22 Jan 2023