Objectives: To digitally evaluate the color matching ability of a "single-shaded" resin composite versus a "single translucency" resin composite system placed in patients' teeth with different shades, and to compare both of them to a gold standard multi-shaded resin composite system, immediately after placement, after 6 months and after 12 months. Methods: 90 anterior teeth and premolars were selected in patients with class V lesions and categorized into three groups according to teeth shades (S1, S2 and S3). These groups were further subdivided into three subgroups according to restorative material placed in the cavities (M1, M2 and M3). Restoration shades were recorded directly after placement (T1), after 6 months (T2) and after 12 months (T3) and ΔE was calculated. Results: Single-shaded resin composite (M1) recorded significant lower ΔE values wih S1 followed by S2 and S3 respectively (P ≤ 0.05). The color matching ability of the single translucency group-shaded resin composite was inferior to that of the single-shaded resin composite at shade S1 while it was superior to that of the single shade resin composite at shades S2 and S3. Multi-shaded resin composite (M3), generally showed the best results with the three teeth shades compared to the other two materials. Time had no significant effect on color matching of the three types of restorative materials (P ≤ 0.05). Conclusions: The single-shaded resin composite showed more acceptable color matching with lighter teeth shades than darker teeth shades. Multi-shaded resin composite showed superior color matching ability at the three different teeth shades.