Introduction: The use of fluoride for caries prevention has been known for many
decades, as it has the ability to incorporate into the crystalline lattice of dental hard
tissues, resulting in a tissue less soluble in acidic environment. Other alternatives for
preventing dental caries are metal ions; Nano Silver Fluoride (NSF). The laser–fluoridation
combination was introduced as a technique that combines the application of
fluoride varnish along and laser. Aim: This study aimed to evaluate and compare the
effect of diode laser when irradiated at diffirent powers and when used either before or
after fluoride varnish application on the longevity of fluoride release using ion selective
electrode, from three different fluoride varnishes (in vitro study): Enamel pro varnish,
Clinpro XT varnish and Nano Silver Fluoride. Material and Methods: 72 samples
were collected, and then divided into 3 groups: Group Ⅰ: Enamel pro, Group Ⅱ: Clinpro
XT and GroupⅢ: Nano Silver Fluoride (NSF). Each group was subdivided according
to diode laser application into 3 subgroups, then samples were placed individually in
a test tube containing artificial saliva. Fluoride release was measured by ion selective
electrode for fluoride. Results: Clinpro XT had the highest amount of fluoride release
followed by Enamel pro. Meanwhile, NSF didn`t release a significant amount of fluoride.
There was a statistically significant difference in fluoride release when diode laser
was irradiated at 5 Watt, after Enamel pro and Clinpro XT application. However, no significant
effect for diode laser irradiation on NSF was found when used either before or
after NSF treatment. Conclusion: Enamel pro and Clinpro XT can be used efficiently
as fluoride varnishes. Diode laser irradiatio