ABSTRACT
Introduction: Vital pulp therapy has been known as one of the treatment options
to preserve pulp vitality after being exposed by trauma or caries. Aim: This experiment
explored the effect of injectable-Platelet Rich Fibrin on marginal adaptation of two pulp < br />capping agents (Mineral Trioxide Aggregate and Bioactive Bone Graft). Materials and
methods: A total of 64 teeth were used out of 8 healthy male beagle dogs. The teeth
were randomly assigned into four groups, they were exposed and capped with different
capping agents. Group A; capped with Mineral Trioxide Aggregate (MTA), Group B;
capped with MTA+ i-PRF, Group C; capped with Bioactive Bone Graft (BBG), Group < br />D; capped with BBG+i-PRF. Finally the access cavity was restored with Intermediate
Restorative Material (IRM). At each predetermined interval, the dogs were sacrificed
(1 month, and 3 months). The samples were then prepared for electron microscopic
scanning evaluation. To compare between the gap percentage of four groups at each
interval, Kruskal-wallis test; was used. Mann-Whitney U test; was used to pair-wise
comparison when Kruskal-wallis test is significant. Bonferroni's correction was utilized
for the pair-wise comparisons. Statistical significance was considered at P < .05.
Results: The data revealed that after one and three months the best values were recorded
in groups B (MTA+ i-PRF) and D (BBG+ i-PRF), in relation to the lowest gap < br />area between the capping materials and dentin, followed by group C (BBG), with the
least value recorded in group A (MTA). Conclusion: the findings from the current study
suggested that i-PRF provided a better marginal adaptation of either MTA or BBG to
the pulp and dentin, which improved with time from one month to three months.