Introduction: Xenograft play role in osseointegration of immediate dental implant. Aim of the study: to evaluate the efficiency of xenograft (Hypro-oss) in osseointegration of immediate dental implant clinically and radiographically. Patients and methods: This study conducted on 8 patients range from 18-48 years old. 12 immediate dental implants divided into two equal groups; (Control Group): Atraumatic extraction of single rooted tooth or remaining root and immediate placement of dental implant, (Study Group): Atraumatic extraction of single rooted tooth or remaining root and immediate placement of dental implant and sealed with Hypro-Oss bone graft material. Clinical examinations done for all patients prior to surgery include examination of oral and para oral tissues and evaluation the intermaxillary space and the type of occlusion. Radiographic evaluation using CBCT done in the intervals 15, 90, 180 and 270 days postoperatively to measure the bone density of the formed bone between living bone and the implant surface. Result: All the patients showed no signs or symptoms of pain, tenderness, redness or inflammation of soft tissue around the inserted implant site. Normal healing process of the soft tissue and bone around the implant. All patients continued the follow up period. Radiographic evaluation showed significant higher bone density in study group than control group after 15, 90, 180 and 270 days. Conclusion: With the use of Hypro-Oss bone graft, the bone density around the implant showed increase in values.