Field experiment was carried out at the Experimental Farm, Faculty of Agriculture, Al-Azhar University, Assiut, Egypt during the two successive seasons of 2020 and 2021 to determine the impact of cattle manure as organic fertilizer at 0, 5, 10 and 15 m3/feddan (feddan = 4200 m2) and foliar spray with some stimulant substances namely, moringa leaf extract at 0, 10, 20 g/L, yeast extract at 5, 10 g/L, garlic extract at 25, 50 ppm and seaweeds extract at 1, 2 ml/L, as well as their interactions on the growth, seed yield, guran percentage and guran yield of guar (Cyamopsis tetragonoloba L. Taub) plants. The obtained results showed that supplying plants with cattle manure at all levels resulted in a significant increase in growth traits (plant height, branch number/plant and herb dry weight/plant), seed yield/plant and per feddan, guran percentage and guran yield/plant and per feddan, except for the high level (15 m3/feddan) concerning plant height, in both seasons. The moderate level of cattle manure (10 m3/feddan) gave the most effective treatment in augmenting these parameters. Foliar spray with all examined stimulant substances at all concentrations led to a significant augment in all studied characteristics, except for yeast extract at 5 g/L regarding plant height and herb dry weight/plant, in the two seasons, and, also for branch number/plant, in the first season. The most effective treatments in increasing growth aspects were detected by spraying seaweeds extract at 2 ml/L followed by garlic extract at 50 ppm. Moreover, foliar spray with 2 ml/L seaweeds extract proved to be more effective in augmenting seed yield/plant and per feddan, guran percentage and guran yield/plant and per feddan than those given by other treatments and control. Clearly, the interaction effect between the two studied factors was statistically significant on all examined parameters. In this concern, the most combined treatments led to a significant increase in the tested aspects. Obviously, the most effective treatments were obtained when the addition of cattle manure at the moderate level (l0 m3/feddan) with seaweeds extract at 2 ml/L or with garlic extract at 50 ppm.