Despite the geographical and cultural convergence and the strategic depth that connects Egypt and the countries of the Nile Basin, the value of trade exchange between Egypt and these countries is considered weak, and does not correspond to the desired volume and value of trade, especially the value of Egyptian exports. Results: The value of the net trade balance took a general and statistically increasing trend, and the annual increase amounted to about $ 27.56 million, with an annual increase rate of about 5.03%, and it was found that the average rate of net exchange between Egypt and the Nile Basin countries amounted to about 85.69%. During the same period, while the rate of change during the period reached about -8.54%, which reflects the trend of trade exchange during the study period in favor of the Nile Basin countries, despite the fact that there is a trade surplus in relation to Egypt. The results showed: The previous results show: the existence of an apparent comparative advantage for Egyptian exports during the study period, and both the market share rate and the apparent comparative advantage coefficient of the Egyptian exports to the Nile Basin countries were shown in the years 2017, 2018, 2019, which indicates the interest of the Egyptian state in this The important file in the recent period, thus increasing the volume of trade and economic cooperation between Egypt and the Nile Basin countries. The results revealed that the most important factors affecting the movement of Egyptian exports to the Nile Basin countries (2006-2019), which turned out to be as follows, Q1: The population of the Nile Basin countries (one million people), Q2: The total value of the national income of the Nile Basin countries (Billion dollars), Q3: The total value of the GDP of the Nile Basin countries (billion. Dollars), Q4: The total value of the GDP of Egypt (billion dollars), Q5: the exchange rate of the Egyptian pound against the US dollar (pounds), and it has been found that there is a relationship The two factors are in agreement with economic logic and statistically significant between the two factors of the total value of Egypt's GDP, the exchange rate of the Egyptian pound against the US dollar (pounds), and the elasticity of each of them was estimated at 3.15.292, respectively, and the most important of these two factors affected the increase in exports It is the GDP of Egypt and that there is a direct relationship between them.