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245592

Novel, Successful Coating for Ln doped UCNPs in Biomedical Applications and Experimental Verification of Field Enhancement based on Surface Texturing

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Last updated: 04 Jan 2025

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Abstract

Upconverting nanoparticles (UCNPs) have been of crucial significance in multiple applications involving photochemical, biomedical and optical ones. For the biomedical applications, one main problem that always stands as a challenge, hindering the upconversion scheme from being deployed inside human cells, is the challenging trade-offs among biomedical and field enhancement requirements imposed by the biomedical design constraints that deprive the UCNPs from field enhancement. Another challenge is imposed due to the constraint on the material choice that should achieve the required targeting, treatment/imaging, and electromagnetic design objective without any harm threatening the human body, which involves the dose limited by biodegradability and biocompatibility of the material. Although multiple field enhancement and manipulation techniques have been applied to UCNPs, there has never been a generic, material independent field enhancement method that could be invoked in biomedical applications without harming the human body despite achieving the required dose. This is a global transformation in the field of photoluminescence (PL) enhancement where there are constraints in the material, especially in biomedical applications, which has been the focus of this work. A novel, broadband, material-independent field enhancement mechanism is verified in lanthanide doped UCNPs through a novel, successful coating method that overcomes another worldwide challenge of surface texturing without lithography.

DOI

10.21608/iugrc.2021.245592

Keywords

photoluminescence, Upconverting Nanoparticles, field enhancement, surface texturing, experimental

Authors

First Name

Noha

Last Name

A.

MiddleName

S.

Affiliation

The American University in Cairo, Egypt.

Email

noha.abouqara@gmail.com

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First Name

Usama

Last Name

Abdelmohsen

MiddleName

Ramadan

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

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Orcid

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First Name

Ahmed

Last Name

Elsayed

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, 7 Universities Zone, New Minia 61111, Egypt.

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-

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Volume

5

Article Issue

5

Related Issue

34928

Issue Date

2021-08-01

Receive Date

2022-06-22

Publish Date

2021-08-01

Page Start

133

Page End

136

Link

https://iugrc.journals.ekb.eg/article_245592.html

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https://iugrc.journals.ekb.eg/service?article_code=245592

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245,592

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Original Article

Type Code

762

Publication Type

Journal

Publication Title

The International Undergraduate Research Conference

Publication Link

https://iugrc.journals.ekb.eg/

MainTitle

Novel, Successful Coating for Ln doped UCNPs in Biomedical Applications and Experimental Verification of Field Enhancement based on Surface Texturing

Details

Type

Article

Created At

22 Jan 2023