ABSTRACT
This experiment was to evaluate the effects of urea molasses mineral block
(UMMB) supplementation on subchronic toxicity in indigenous goat kids. Twenty
growing goat kids were randomly assigned to receive ad libitum rice straw and berseem
hay (Trifolium alexandrinum L.) (40:60). Group I was fed concentrate mixture (0.1
kg/d). Group II was supplemented with UMMB (0.2kg/d). The experiment lasted for 90
days. There was significant (p<0.05) decrease in serum sodium (60.68mEq/L), increase
in serum potassium (34.50 mEq/L) and increase in activity of Aspartate
aminotransferase (340.42U/L) and Alanine aminotransferase (164.96 U/L) which were
observed in kids of group II in comparision to the control (group I). On
histopathological examination mild degenerative changes in kidney of group II with
congestion in intertubular vessel, granular cytoplasm of the epithelial cells in proximal
convoluted tubules (PCT) and distal convoluted tubules (DCT), necrosis and swelling
of the epithelial cells, congestion of vessels and cloudy swelling was observed in PCT
and DCT. Albuminious mass was also present in tubule. On histopathological
observation of liver of kids of group II edema in liver parenchyma and proliferation of
fibrous tissue in periportal area was observed.