This study aims to produce an alternativefuel from optimized mixture of municipal solid waste residuals, non-hazardous industrial wastes and agricultural residues with a production plant design and detailed economic feasibility study. Waste types examined in this study are rice straw, cotton stalks, plastics, wood, used tires, olive pomace oil, paper, and dried digested sludge. Optimum mix selection criteria are; calorific value with a weighting factor 30%, density 15%, moisture content 15%, oxygen content 10%, and gas emissions 30%. Eight mixes are investigated and the optimum mix was 23% rice straw, 19.52% wood, 24.58% plastics, 18.43% cotton stalks, and 14.47% used tires. The optimum mix has a calorific value of 5272 cal/g, density of 311 kg/m³, and moisture content of 1.94%. The proposed selling price of the alternative fuel produced is 1200 LE per ton covering all capital costs and operational & maintenance costs.