This study was performed to investigate the biochemical alteration of Biochemical effects of Helicobacter pylori infection on iron metabolism and its related components in human. Ninety Patients (male & female) were divided according to ages into four groups; the group (I) contained 20 healthy individuals aged (10 – 65) years used as control for all groups. Group (II): consisted from 30 infected patients with Helicobacter pylori aged (10 –25) years. Group (III): consisted from 30 infected patients with Helicobacter pylori aged (25 – 40) years. Group (IV): consisted from 30 infected patients with Helicobacter pylori aged (40- 65) years.
The blood samples were collected and the obtained results revealed that, Significant increases in serum gastrin amylase, ammonia, total iron binding capacity (TIBC), transferrin, total cholesterol, triacylglycerols (Tg), low density lipoprotein–cholesterol (LDL), very low density lipoprotein–cholesterol (VLDL), high density lipoprotein–cholesterol (HDL) Furthermore, significant decreases were in plasma serum iron, Ferritin, haptoglobin, Vitamin B₁₂, leptin and HDL in compared to control group. From the obtained results it could be concluded that, we must take car from Helicobacter pylori.