Background: GERD is the most common upper gastroesophageal disorder in the Western population. A number of strategies have been recommended to prevent this problem. Aim of the Work: to compare the Nissen fundoplication with partial anterior fundoplication. Patients and Methods: The present comparative study included thirty patients who had symptomatic GERD admitted in pediatric surgery department ,Al-Azhar University hospitals and all patients submitted to preoperative clinical evaluation and investigations. Patients were randomly allocated to undergo either laparoscopic Nissen fundoplication (group I) or laparoscopic partial anterior fundoplication (group II). All patients in our study signed a consent form. Results: there was no significant difference between both groups as regard intraoperative complications, the hospital stay. But there was a significant difference between both groups in regarding operative time in favor of partial anterior procedure. After 1, 3, 6 months there is no significant difference between both groups as regarding to heartburn and regurgitation . As regarding to post operative dysphagia After 3 months there was a highly significant difference between both groups as regards dysphagia in favor of partial anterior fundoplication as dysphagia was significantly less with partial anterior fundoplication. After 1, 3 and 6 months gas bloating less common with partial anterior fundoplication but without significant differences between both groups. Conclusion: Partial anterior fundoplication seems safe and effective in treating the symptoms of GERD as Nissen fundoplication including patients with severe forms of the disease. Its technique is simpler and takes shorter time to perform.