Background: Intrauterine insemination (IUI) is a common reproductive treating for unexplained infertility (UI). To achieve conception, washed sperm is put into the uterine cavity. The success rate of IUI with simultaneous ovulation induction is a hot topic of discussion. In cases of unexplained infertility, hydrotubation has resulted in a significantly higher conception rate.
Aim of the study: to compare the effect of simple hydrotubation with 20 ml of saline and lidocaine one day before IUI with no hydrotubation on the conception rate in patients with unexplained infertility.
Patients and methods: This prospective randomized controlled trial included 214 women with unexplained infertility who attended Alzhar University Hospitals' Gynecology Outpatient Clinics.
Result: There was a statistically substantial variation between the two groups. Treatment results. Clinical pregnancy was observed in 50 (46.7 %) of included patients in group A. No OHSS was observed in both groups.
Conclusion: Hydrotubation with lidocaine one day before to IUI is a safe and well-tolerated technique. When comparing to nohydrotubation, it resulted in a greater conception rate, with a substantial change for couples with unexplained infertility. No significant complications of the procedure were reported with no to mild pain according to VAS score. However, More research is needed to look at the dose-dependency of Lidocaine hydrotubation and the impact of multiple sessions on the incidence of clinical gestation in these individuals.