Background: Idiopathic intracranial hypertension (IIH), also defined as primary pseudotumour cerebri condition, is a neurological disorder marked by elevated intracranial pressure (ICP) and papilledema with no recognized etiology.
Aim of the study : To evaluate papilledema in individuals associated with idiopathic intracranial hypertension according to Frisen grading based on descriptive features and its correlation with retinal nerve fibre layer (RNFL) thickness using spectral domain optical coherence tomography(OCT).
Patients and Methods: Our study is a cross sectional observational study that was demonstrated on 48 eyes with papilledema due to IIH. Patients were undergone full ophthalmolgical examination with emphasis on optic disc features and OCT imaging of peripapillary RNFL of optic nerve head (ONH).
Results: with statistically analysis of RNFL thickness in 4 quadrants showing that follow ISNT rule . The mean of average RNFL in mild papilledema is (98.30 ± 24.97), in moderate (162.69 ± 36.96) and in severe (247.40 ± 37.69). That indicates progression of papilledema highly significant correlated with increasing RNFL thickness. Average RNFL thickness values were analysed under ROC curve to give cut off points help as an indicator for diagnosis clinical severity of papilledema .
Conclusion: OCT has the potential to be a useful imaging tool in the identifying and monitoring of IIH, especially when combined with other clinical data. It is now being used in concert with other imaging techniques and clinical factors to detect early variations in the ONH and retinal layers before and after intracranial hypertension therapy.