Background: This condition is known as preeclampsia, which is characterized by new-onset hypertension after twenty weeks of gestation with indications of organ damage; the potential maternal and neonatal consequences of preeclampsia are considerable.
Aim of the study : The study's goal is to determine the function and efficiency of low molecular weight heparin in avoiding severe preeclampsia.
Patients and Methods: The study is randomized, interventional study and carried out on cases of high risk of pre-eclampsia at obstetrics, gynecology department al-azhar university hospitals. Our study was done on one hundred participants of high risk of pre-eclampsia separate into 2 groups; Group 1 (study group): in accordance with standard regimen, 50 patients got low molecular weight heparin. Group 2 (control group): contain 50 cases had received usual regimen only.
Results: The current results show statistically significant differences between groups according to patient's clinical improvement, APGAR score and NICU admission with more improvement in patients who received low molecular weight heparin in accordance with usual regimen when it compared to other group which contain cases received usual regimen only (control group).
Conclusion: low molecular weight heparin is effective in preventing development of severe preeclampsia in patients with mild preeclampsia on expectant management of this resulting in less maternal, fetal and neonatal morbidity and mortality.