Background - Breast cancer (BC) has been the most frequent cancer among women worldwide, and it is the leading cause of cancer-related death. Nowadays, numerous surgical treatments are extensively employed in the management of BC, including full surgical resection of the breast (mastectomy) and breast conserving operations (quadrantectomy), which may or may not be accompanied by radiation.
Aim - to analyze the optimal surgical management for early breast cancer through the comparison between quadrantectomy and modified radical mastectomy.
Patient and Methods – A total of 60 women suffering from early breast cancer were diagnosed using precise criteria and were gathered from January 2021 to January 2022. In this study, we classified 2 groups: Group A: 30 patients prepared for quadrantectomy and Group B: 30 patients prepared for modified radical mastectomy.
Results - there is no significant difference between the two groups regarding age and BMI, tumor size and site, mass site in the breast, histopathology findings, grade and stage, complications and recurrence. When compared to the quadrantectomy group, the mastectomy group had significantly higher surgical time, loss of blood, and hospital stay. Disease free survival after 12 months in group A was 82.5% and in group B it was 94.2%, with a log rank test of 0.861.
Conclusion - When compared to modified radical mastectomy, quadrantectomy was more efficacious in the management of early-stage breast cancer, involving less surgery time and intraoperative blood and a reduced hospital length of stay.