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259911

Relationship between anemia and biochemical parameters of mineral bone disorders in chronic kidney disease patients

Article

Last updated: 22 Jan 2023

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Abstract

Background: Anemia, electrolyte disturbances and mineral bone disorders are common outcomes of chronic kidney disease (CKD). We aimed to asses relationship between anemia and mineral bone disorder (MBD) parameters in stages 3-5 CKD on conservative treatment patients.
Results: The study revealed a statistically significant association between Hb and eGFR, and also showed a statistically significant negative relationship (p value = 0.001) (r = -0.38) between Hb and serum creatinine. It also revealed a semi-inverse relationship between serum parathormone (iPTH) and hemoglobin level in blood between CKD. Whenever there is an increase in the serum iPTH reflects the decrease in the level of hemoglobin in the blood of the study sample of patients with chronic kidney disease. One of the important statistical results indicated by the study is that blood phosphate is linked to low hemoglobin in kidney patients. Our study agreed with studies that show that vitamin D deficiency is closely related to low hemoglobin level in CKD patients. The higher the calcium level, the lower the hemoglobin level. We found that increased blood calcium is associated with a lower hemoglobin level.
Conclusion: Our study showed the significant association between CKD-BMD and anemia. It also showed that increased serum phosphate, parathyroid activity, severe deficiency in vitamin D and a high incidence of anemia among patients with chronic kidney disease.

DOI

10.21608/aimj.2022.130263.1888

Keywords

Anemia, Chronic Kidney Disease, Mineral bone disorder

Authors

First Name

Mustafa

Last Name

Abo Sayed

MiddleName

Gamal

Affiliation

Internal medicine, faculty of medicine, Alazhar university,Cairo,Egypt

Email

mustafagamal51993@gmail.com

City

Cairo

Orcid

-

First Name

Hani

Last Name

Ismail

MiddleName

-

Affiliation

Internal medicine,faculty of medicine,Alazhar university ,cairo,Egypt

Email

haniismail52@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Saad

MiddleName

Alaa

Affiliation

Internal medicine,faculty of medicine,Alazhar university ,cairo,Egypt

Email

drahmedalaa555@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Farouk

MiddleName

-

Affiliation

Clinical Pathology,faculty of medicine,Alazhar university ,cairo,Egypt

Email

faroukmohamed301@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

9

Related Issue

36971

Issue Date

2022-09-01

Receive Date

2022-03-29

Publish Date

2022-09-01

Page Start

11

Page End

15

Print ISSN

2682-3381

Online ISSN

2682-339X

Link

https://aimj.journals.ekb.eg/article_259911.html

Detail API

https://aimj.journals.ekb.eg/service?article_code=259911

Order

3

Type

Original Article

Type Code

710

Publication Type

Journal

Publication Title

Al-Azhar International Medical Journal

Publication Link

https://aimj.journals.ekb.eg/

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Details

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Article

Created At

22 Jan 2023