Background: The most common malignancy in the reproductive system of female is the Endometrial carcinoma, that is represent the fourth common women cancer in the world. The first line to treat any disease that's be in diagnosing tools.

Aim of the study: we aimed from this study to enhancing the role of diffusion weighted magnetic resonance imaging (MRI) to detect the endometrial cancer.

Patients and Method: The study included 25 patients referred from the gynecological outpatient clinic to assess the endometrium, in range between 45-75 years old with dysfunctional uterine bleeding, bleeding of post-menopausal, and taken tamoxifen through 1.5 tesla diffusion weighted MRI Achiva Philips 32 channels.

Results: Aging patients was 59.96 ± 7.9 years old, 88% presented with postmenopausal bleeding and 12% menorrhagia, which 79% histopathological adenocarcinoma 16% unspecific carcinoma, grading tumor was grade I in 52%, 28% grade II, and 20% in grade III, In DW1 images, we found that high signal was present among all selected patients (25 females).

Conclusion: The most important and accurate imaging technique in endometrial cancer staging is the MRI diffusion weighted more than T2W conventional images alone.