Background: Bile duct injury following cholecystectomy is an iatrogenic catastrophe which is associated with significant perioperative morbidity and mortality, reduced long-term survival and quality of life, and high rates of subsequent litigation. The aim of this article was to review the management of bile duct injury after cholecystectomy. Objective: study the recent trend in management of biliary leakage due to bile duct injuries during and after cholecystectomy and to set up organized protocol for managing with bile leaks. Patients and Methods: This is a Retrospective study was performed at the Department of General Surgery, Al-Azhar University Hospital, Cairo between February 2020 to December 2021. This study was a case series of 1250 patients who underwent LC. Twenty five patients with a bile leak following laparoscopic cholecystectomy were recorded consecutively. Twenty five cases with Cholecystitis (acute and chronic) who underwent LC and suffering from postoperative bile leak, were included in this study. Results: In our study Patients were managed gradually, starting with the minimally invasive endoscopic treatment alone or with percutaneous drainage technique to the more invasive surgical technique. Conclusion: Endoscopic treatment replaced surgery in all simple postoperative bile leak cases as an identical definitive treatment.Surgical treatment was the definitive treatment of complex postoperative bile leakage; however, endoscopy was a mandatory complementary tool in the initial management.