Background: Breast cancer is the most frequent type of cancer in women, and it is also the main cause of cancer mortality in women. Through the usage of neoadjuvant chemotherapy, surgical therapy for breast tumor has progressed from highly radical, debilitating operations to less invasive techniques.
Objective: The goal of this study is to see if conservative breast surgery is feasible and has a good oncologic result in females who had breast cancer who were downstaged via neoadjuvant chemotherapy.
Patients and Methods: This non-randomized prospective study will include twenty (20) women suffering from cancer who will undergo neoadjuvant chemotherapy in order to reduce the cancer's stage and render it suitable for preservation, management, and treatment at Al-Hussein and Bab-elshaaria Hospitals.
Results: Women having breast cancer had a significant difference in tumor size before and after chemotherapy. All of them had free margins after conservative breast surgery with an intraoperative frozen portion, and the aesthetic result was satisfactory. Following six months of follow-up, there was no local recurrence.
Conclusion: It was discovered in this research that neoadjuvant chemotherapy is efficient and useful in downstaging the tumor size as well as axillary lymph nodes in breast cancer women. Also, good results were obtained regarding the local recurrence throughout the short time of this research.