Background; Cicatricial alopecia is a form of scarring alopecia caused by a collection of diseases in which the hair follicle unit is destroyed and then replaced with fibrous tissue., Aim and objectives: was to assess efficacy of autologous nano fat in hair transplantation by FUE in cicatricial alopecia. Subjects and methods: This was a Randomized clinical trial for 20 patients presenting with scarring alopecia. The cases were recruited from Dermatology outpatient clinic of Al-Azhar University Hospitals from March 2021 to November 2021. Result Between the studied groups, there was a statistically significant difference. with more improvement among patients presenting with cicatricial alopecia and were treated by autologous emulsified fat then hair transplantation by FUE after 1 month. Conclusion; In conclusion, compared with hair transplantation by FUE only, autologous emulsified fat followed by hair transplantation by FUE is more effective in treatment of cicatricial alopecia concerning number of hair grafts remaining after 6 months . Also, needs less number of hairs transplanted with great improvement and yields satisfactory postoperative results.