Background: Postpartum hemorrhage (PPH) is the most basic reason of maternal morbidity and mortality worldwide. Uterine atony is the most common reason of immediate heavy PPH.
Objective: To compare of I.V carbetocin as a long acting oxytocic drug and a combination of intraoperative oxytocin and ergometrine I.V for inhibition of PPH after cesarean delivery.
Patients and methods: a randomized prospective study that was carried out at Alhwamdya General Hospital. After receiving written consent, 100 women were chosen from the obstetrics and gynecology outpatient clinic between May 2020 and February 2021.
Results: In terms of maternal adverse impacts , there was a substantial change among the two groups , 28 % of population of Oxytocin & ergometrine group experienced elevated systolic /diastolic blood pressure more than 10 mmHg from preoperative reading ,while patiants who received carbetocin only show no signficant rise in blood pressure. There was a substantial change in estimated blood loss among the two groups, favouring the carberocin group. Other than that, there was no important change between the two groups in terms of the frequency of PPH, the requirement for extra uterotonic medications, or the incidence of other side impacts like headache.
Conclusion: According to the findings, simultaneous intravenous carbetocin is beneficial in preventing atonic post-partum haemorrhage after caesarean surgery. It's just as effective as a mix of I.V syntocinon and ergometrine. Compared to the combination of syntocinon and ergometrine, carbetocin alone had less side effects on the mother, such as high blood pressure, nausea, and vomiting.