Background; decreased rates of gestation are detected in cases with uterine space irregularities. The correction of these irregularities was accompanying with better rates of gestation. Diagnostical hysteron-scopy could be accomplished with negligeable distress and higher sensitivity and specificity in assessment of the uterine space, Aim and objectives; to assess the role of hysteron-scopy in diagnosing the abnormalities of the uterine-space among females having secondary infertility, Subjects and methods; This work was conducted on138 cases having secondary infertilities with no suspected uterine defect at the gynecological outpatient clinic in Al-Hussein and Sayed Galal University Hospital, Al-Azhar University, Result; Majority of the patients underwent hysteroscopy as per infertility workup (77.5%), Conclusion; hysteroscopy was the most precise diagnostical examination for lesions in comparison with ultra-sonography. The technique was of limited usage in the diagnosing of intra-uterine adhesions and some uterine deformities, while its global consequences in diagnosis of uterine deformities were better than those attained by ultrasonography