Abstract
Background: Androgenic alopecia is a common condition that is defined by the progressive conversion of terminal hairs to villus hairs in a unique distribution in both males and females. Therefore, autologous fat injection is tried as a new promising treatment for AGA.

Material and Methods: A prospective randomized controlled study was done among 30 patients have androgenic alopecia from February 2021 to October 2021. .Patients were separated into two groups of equal size; Group A which is treated by autologous Nanofat injection and Group B which is treated by stromal vascular fraction injection.
Results: The present study showed great improvement in 1 participants (6.7%) in group A and 4 participants (26.7%) in group B. moderate improvement present in 2 participants (13.3%) in group A and 7 participants (46.7%) in group B. slight improvement occurred in 8 participants (53.3%) in group A and 2 p participants (13.3%) in group B. after 6 months of treatment No response occurred in 4 participants (26.7%) in group A and 2 participants (13.3%) in group B. As regard hair count/cm2 , it was 129.9 ± 13.7 /cm2 before treatment and it was 139.5 ± 18.1 /cm2 after treatment in group A. While it was 129.5 ± 10.8 /cm2 before treatment and it was 158.1 ± 21.02 /cm2 after treatment, all nonresponsive participants had higher grades of AGA.

Conclusion: Both Nanofat and SVF were effective in treatment of Androgenic alopecia with statistically significant difference as regard increase in hair density, clinical improvement and patient satisfaction.