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226131

Multi-detector Computed Tomography Versus Upper Gastrointestinal Endoscopy in Diagnosis and Grading of Esophageal Varices in Egyptian Cirrhotic Patients

Article

Last updated: 22 Jan 2023

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Abstract

Background: Cirrhosis is often complicated by esophageal varices (EVs). The use of upper GI endoscopy (EGD) as a screening method is limited regarding invasiveness, expensive, needs sedation as well as patient's poor acceptance of the procedure. In contrast, Multidetector Computed Tomography (MDCT) imaging is non-invasive, does not necessitate sedation, and allows accurate assessment of variceal site and size. It is also better tolerated by patients than EGD.
Aim of the work: To assess the efficacy of MDCT in evaluating the EVs.

Patients and method: A prospective cross-sectional study was carried out. in the hepatogastroenterology and infectious disease department and department of radiology, Al-Azhar university hospitals. From June 2021 to November 2021, fifty patients attended the outpatient clinic who had cirrhosis due to chronic HCV were enrolled in the study on a prospective basis, aged 24 to 73 years old. The studied patients were subjected to history taking, clinical examination, MDCT, and EGD.

Results: The cases were separated into three groups based on the CT findings: group I, which included 11 patients with no EVs (22%), group II, which included 11 patients with low-risk varices (22%), and group III, which included 28 patients with high-risk varices (56%). The total CT sensitivity for detecting EVs was 92.8%, with 100% specificity, 100% PPV, and a 72.7% NPV. The MDCT sensitivity for high-risk EVs cases (100%) was greater than that for low-risk EVs cases (72.7%).

Conclusion: MDCT is an excellent diagnostic alternative to conventional EGD for detecting and grading EVs in cirrhotic patients.

DOI

10.21608/aimj.2022.106046.1659

Keywords

Cirrhosis, Endoscopy, Computed tomography, Portal Hypertension

Authors

First Name

Mahmoud

Last Name

Ali

MiddleName

Madeh

Affiliation

Hepatogastroenterology and Infectious diseases department, Faculty of Medicine, Al-azhar university, Cairo, Egypt.

Email

mahmoudouf4@gmail.com

City

Cairo

Orcid

-

First Name

Mohammed

Last Name

Afify

MiddleName

Amer

Affiliation

Hepatogastroenterology and Infectious diseases department, Faculty of Medicine, Al-azhar university, Cairo, Egypt.

Email

amerlivercenter@azhar.edu.eg

City

Cairo

Orcid

-

First Name

Osama

Last Name

Abdelrazek

MiddleName

Mostafa

Affiliation

Hepatogastroenterology and Infectious diseases department, Faculty of Medicine, Al-azhar university, Cairo, Egypt.

Email

osamamos67@gmail.com

City

cairo

Orcid

-

First Name

mohamed

Last Name

elfeshawy

MiddleName

salah

Affiliation

Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Email

mohamedelfeshawy@azhar.edu.eg

City

cairo

Orcid

-

First Name

Ahmed

Last Name

Abdelnaby

MiddleName

Mohammed

Affiliation

Hepatogastroenterology and Infectious diseases department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Email

dr_a.abdelnaby@yahoo.com

City

cairo

Orcid

-

Volume

3

Article Issue

3

Related Issue

32736

Issue Date

2022-03-01

Receive Date

2021-11-15

Publish Date

2022-03-01

Page Start

35

Page End

43

Print ISSN

2682-3381

Online ISSN

2682-339X

Link

https://aimj.journals.ekb.eg/article_226131.html

Detail API

https://aimj.journals.ekb.eg/service?article_code=226131

Order

6

Type

Original Article

Type Code

710

Publication Type

Journal

Publication Title

Al-Azhar International Medical Journal

Publication Link

https://aimj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023