Background: Among the most prevalent surgical procedures in the world is the cesarean section (CS). Postoperative analgesia is too important to prevent unwanted side effects like venous thromboembolism, respiratory complications, and a longer stay in the hospital. Pethidine was used as adjuvants to local anesthesia to improve the quality of TAP block for caesarian section.
Objective: To evaluate and compare the effects of pethidine in combination with bupivacaine on the quality of the TAP block for caesarian sections.
Patients and methods: A total of 60 patients with American Society of Anesthesiologists (ASA) physical status I or II who were scheduled for Cesarean deliveries were enrolled in this randomized, prospective, double-blind clinical trial. Al-Azhar University Hospitals were used to conduct the research (Al-Husein and Sayed Galal Hospitals). They have been split into 2 groups of equal size: patients in Group (B) received ultrasound-guided TAP block with 20 ml of bupivacaine 0.25 % bilaterally, while patients in Group (BP) received ultrasound-guided TAP block with 20 ml of bupivacaine 0.25 % and 50 mg of pethidine bilaterally.
Results: The BP group's VAS score was significantly lower at 8 and 12 hours. The time to the first analgesic dose in the BP group was significantly longer than in the B group.
Conclusion: Addition of pethidine was a useful adjuvant to bupivacaine for improving quality of TAP block for caesarian section.